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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LINEZOLID
| LINEZOLID | ANTIINFECTIVES | ORAL INTRAVENOUS | Cmax 44.8 MICROMOLAR Tmax 0.51 HOUR F 100 PERCENT VD 45 LITER PPB 31 PERCENT Cl 7.38 LITER / HOUR HT 4.8 HOUR | 50S RIBOSOMAL SUBUNIT PDB 4WFA (THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT OF STAPHYLOCOCCUS AUREUS IN COMPLEX WITH LINEZOLID) LIGAND CODE = ZLD (link to the list of PDB complexes) Download experimental 3D coordinates of ZLD with added hydrogens | Unknown more at DrugCentral | EMA | |||
