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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ALOSETRON
| ALOSETRON | METABOLISM | ORAL | Cmax 30.6 NANOMOLAR Tmax 1 HOUR F 55 PERCENT VD 80 LITER PPB 82 PERCENT Cl 36 LITER / HOUR HT 1.5 HOUR SOLUBILITY OF 61 MILLIGRAM / MILLILITER IN WATER | 5-HYDROXYTRYPTAMINE 3 RECEPTOR | 5-hydroxytryptamine receptor 3A UNIPROT P46098 HTR3A more at DrugCentral | EMA | |||
