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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DEXMEDETOMIDINE

DEXMEDETOMIDINE


ATC N05CM18

NERVOUS SYSTEM
ADRENERGIC ALPHA AGONISTS
HYPNOTICS AND SEDATIVES

INJECTION INTRAVENOUS BUCCAL SUBLINGUAL

VD 118 LITER

PPB 94 PERCENT

Cl 39 LITER / HOUR (72 KILOGRAM)

HT 2 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

ALPHA-2A ADRENERGIC RECEPTOR

Alpha-2A adrenergic receptor UNIPROT P08913 ADRA2A -- Alpha-2B adrenergic receptor UNIPROT P18089 ADRA2B

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