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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LEVOBUPIVACAINE
| LEVOBUPIVACAINE BUPIVACAINE | NERVOUS SYSTEM | INJECTION SPINAL IMPLANTATION INFILTRATION PERIARTICULAR | VD 54.6 LITER PPB 94 PERCENT Cl 16.7 LITER / HOUR HT 3.1 HOUR SOLUBILITY SOLUBLE IN WATER | ACETYLCHOLINE RECEPTOR NMDA RECEPTOR 5HT3 PDB 8I5B (STRUCTURE OF HUMAN NAV1.7 IN COMPLEX WITH BUPIVACAINE) LIGAND CODE = OJ0 (link to the list of PDB complexes) Download experimental 3D coordinates of OJ0 with added hydrogens | Sodium channel protein type 4 subunit alpha UNIPROT P35499 SCN4A more at DrugCentral | EMA | |||
