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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CEVIMELINE
| CEVIMELINE | NERVOUS SYSTEM | ORAL | Tmax 1.75 HOUR VD 390 LITER (65 KILOGRAM) PPB 20 PERCENT Cl 54 LITER / HOUR (EQN) HT 5 HOUR SOLUBILITY VERY SOLUBLE IN WATER | MUSCARINIC ACETYLCHOLINE RECEPTOR M3 MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | Muscarinic acetylcholine receptor M1 UNIPROT P11229 CHRM1 -- Muscarinic acetylcholine receptor M3 UNIPROT P20309 CHRM3 more at DrugCentral | EMA | |||
