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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TELMISARTAN
| TELMISARTAN |
CARDIOVASCULAR | ORAL | Tmax 0.75 HOUR F 58 PERCENT VD 500 LITER PPB 99.5 PERCENT Cl 48 LITER / HOUR HT 24 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | ANGIOTENSIN II RECEPTOR PDB 3VN2 (CRYSTAL STRUCTURE OF PPARGAMMA COMPLEXED WITH TELMISARTAN) LIGAND CODE = TLS (link to the list of PDB complexes) Download experimental 3D coordinates of TLS with added hydrogens | Type-1 angiotensin II receptor UNIPROT P30556 AGTR1 more at DrugCentral | EMA | |||
