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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ARGATROBAN

ARGATROBAN


ATC B01AE03

BLOOD
ANTITHROMBOTIC
ANTICOAGULANTS
PLATELET AGGREGATION INHIBITORS
THROMBIN INHIBITOR (KI = 0.04 MICROMOLAR)

INJECTION INTRAVENOUS

VD 11.3 LITER (65 KILOGRAM)

PPB 54 PERCENT

Cl 20.1 LITER / HOUR (65 KILOGRAM)

HT 0.75 HOUR

THROMBIN

Prothrombin UNIPROT P00734 F2

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