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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| RIVASTIGMINE
| RIVASTIGMINE | NERVOUS SYSTEM | ORAL TRANSDERMAL | Tmax 1 HOUR F 40 PERCENT VD 146.2 LITER (65 KILOGRAM) PPB 40 PERCENT Cl 108 LITER / HOUR HT 1.5 HOUR SOLUBILITY VERY SOLUBLE IN WATER | CHOLINESTERASE | Acetylcholinesterase UNIPROT P22303 ACHE -- Cholinesterase UNIPROT P06276 BCHE more at DrugCentral | EMA | |||
