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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TOLTERODINE (has an active metabolite)
| TOLTERODINE | GENITO | ORAL | Cmax 4.92 NANOMOLAR Tmax 1.5 HOUR VD 113 LITER PPB 96.3 PERCENT Cl 534 LITER / HOUR HT 2 HOUR SOLUBILITY IN WATER 12 MILLIGRAM / MILLILITER | MUSCARINIC ACETYLCHOLINE RECEPTOR | Muscarinic acetylcholine receptor M2 UNIPROT P08172 CHRM2 -- Muscarinic acetylcholine receptor M3 UNIPROT P20309 CHRM3 more at DrugCentral | EMA | |||
