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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
NARATRIPTAN

NARATRIPTAN


ATC N02CC02

NERVOUS SYSTEM
ANTIMIGRAINE
SELECTIVE SEROTONIN AGONISTS
VASOCONSTRICTOR AGENTS

ORAL

Tmax 2.5 HOUR

F 70 PERCENT

VD 170 LITER

PPB 30 PERCENT

Cl 25.7 LITER / HOUR (65 KILOGRAM)

HT 6 HOUR

SOLUBILITY READILY SOLUBLE IN WATER

5-HYDROXYTRYPTAMINE 1D RECEPTOR
5-HYDROXYTRYPTAMINE 1B RECEPTOR

5-hydroxytryptamine receptor 1B UNIPROT P28222 HTR1B -- 5-hydroxytryptamine receptor 1D UNIPROT P28221 HTR1D

more at DrugCentral

EMA

ANSM (in French)

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SIDER side effects

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ChEMBL
BindingDB
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