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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| REPAGLINIDE
| REPAGLINIDE | METABOLISM | ORAL | Cmax 145.5 NANOMOLAR Tmax 1 HOUR F 56 PERCENT VD 31 LITER PPB 98 PERCENT Cl 38 LITER / HOUR HT 1 HOUR | ATP DEPENDANT POTASSIUM CHANNEL PDB 6JB3 (STRUCTURE OF SUR1 SUBUNIT BOUND WITH REPAGLINIDE) LIGAND CODE = BJX (link to the list of PDB complexes) Download experimental 3D coordinates of BJX with added hydrogens | Sulfonylurea receptor 1, Kir6.2 UNIPROT Q09428 ABCC8 more at DrugCentral | EMA | |||
