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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| OLANZAPINE
| OLANZAPINE | NERVOUS SYSTEM | ORAL INTRAMUSCULAR | Tmax 6 HOUR VD 1000 LITER PPB 93 PERCENT Cl 25 LITER / HOUR HT 30 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | 5-HYDROXYTRYPTAMINE 2A RECEPTOR (5HT-2) D(2) DOPAMINE RECEPTOR | D(2) dopamine receptor UNIPROT P14416 DRD2 -- 5-hydroxytryptamine receptor 2A UNIPROT P28223 HTR2A more at DrugCentral | EMA | |||
