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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TAMSULOSIN
| TAMSULOSIN |
GENITO | ORAL | Cmax 101.9 NANOMOLAR Tmax 5 HOUR F 90 PERCENT VD 16 LITER PPB 96.5 PERCENT Cl 2.88 LITER / HOUR HT 14.9 HOUR SOLUBILITY SPARINGLY SOLUBLE IN WATER | ALPHA-1A ADRENERGIC RECEPTOR ALPHA-1B ADRENERGIC RECEPTOR ALPHA-1D ADRENERGIC RECEPTOR PDB 7YMJ (CRYO-EM STRUCTURE OF ALPHA1AAR-NB6 COMPLEX BOUND TO TAMSULOSIN) LIGAND CODE = JGX (link to the list of PDB complexes) Download experimental 3D coordinates of JGX with added hydrogens | Unknown more at DrugCentral | EMA | |||
