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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| AMLEXANOX DISCONTINUED
| AMLEXANOX | METABOLISM | DENTAL TOPICAL | Cmax 402 NANOMOLAR Tmax 2.4 HOUR HT 3.5 HOUR | G PROTEIN-COUPLED RECEPTOR KINASES (GRKS) (PMID25340299) PDB 2KOT (SOLUTION STRUCTURE OF S100A13 WITH A DRUG AMLEXANOX) LIGAND CODE = ANW (link to the list of PDB complexes) Download experimental 3D coordinates of ANW with added hydrogens | Phosphodiesterase 4 UNIPROT P27815 PDE4A more at DrugCentral | EMA | |||
