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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| AZELAIC ACID
| AZELAIC ACID | DERMATOLOGICALS | TOPICAL | Cmax 335 NANOMOLAR F 4 PERCENT HT 0.75 HOUR SOLUBILITY POORLY SOLUBLE IN WATER | DIAMINOPIMELATE DECARBOXYLASE PDB 1TUF (CRYSTAL STRUCTURE OF DIAMINOPIMELATE DECARBOXYLASE FROM M. JANNASCHI) LIGAND CODE = AZ1 (link to the list of PDB complexes) Download experimental 3D coordinates of AZ1 with added hydrogens | 3-oxo-5-alpha-steroid 4-dehydrogenase 2 UNIPROT P31213 SRD5A2 more at DrugCentral | EMA | |||
