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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| MIRTAZAPINE
| MIRTAZAPINE | NERVOUS SYSTEM | ORAL | Tmax 2 HOUR F 50 PERCENT VD 273 LITER (65 KILOGRAM) PPB 85 PERCENT Cl 31.2 LITER / HOUR (65 KILOGRAM) HT 30 HOUR SOLUBILITY SLIGHTLY SOLUBLE IN WATER | ALPHA-2A ADRENERGIC RECEPTOR 5-HYDROXYTRYPTAMINE 2 RECEPTOR 5-HYDROXYTRYPTAMINE 3 RECEPTOR HISTAMINE H1 RECEPTOR | 5-hydroxytryptamine receptor 2A UNIPROT P28223 HTR2A -- 5-hydroxytryptamine receptor 2C UNIPROT P28335 HTR2C more at DrugCentral | EMA | |||
