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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| NISOLDIPINE
| NISOLDIPINE | CARDIOVASCULAR | ORAL | Tmax 9 HOUR F 5 PERCENT VD 357 LITER (65 KILOGRAM) PPB 99 PERCENT Cl 58.5 LITER / HOUR (65 KILOGRAM) HT 9.5 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | VOLTAGE-DEPENDENT CALCIUM CHANNEL | Voltage-dependent L-type calcium channel subunit alpha-1C UNIPROT Q13936 CACNA1C -- Voltage-dependent L-type calcium channel subunit alpha-1D UNIPROT Q01668 CACNA1D more at DrugCentral | EMA | |||
