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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ADAPALENE
| ADAPALENE | DERMATOLOGICALS | TOPICAL | Cmax 1.1 NANOMOLAR HT 17.2 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | RETINOIC ACID RECEPTOR ALPHA RETINOIC ACID RECEPTOR BETA RETINOIC ACID RECEPTOR GAMMA | Retinoic acid receptor beta UNIPROT P10826 RARB -- Retinoic acid receptor gamma UNIPROT P13631 RARG more at DrugCentral | EMA | |||
