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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CARVEDILOL
| CARVEDILOL | CARDIOVASCULAR | ORAL | F 30 PERCENT VD 115 LITER PPB 98 PERCENT Cl 36 LITER / HOUR HT 8.5 HOUR SOLUBILITY PRATICALLY INSOLUBLE IN WATER | BETA ADRENERGIC RECEPTOR ALPHA-1A ADRENERGIC RECEPTOR | Beta-1 adrenergic receptor UNIPROT P08588 ADRB1 -- Beta-2 adrenergic receptor UNIPROT P07550 ADRB2 more at DrugCentral | EMA | |||
