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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
FLUVASTATIN

FLUVASTATIN


ATC C10AA04

CARDIOVASCULAR
HYPOLIPIDEMIC
HYPOCHOLESTEROLEMIC
HMG-COA REDUCTASE INHIBITORS

ORAL

Tmax 1 HOUR

F 24 PERCENT

VD 22.7 LITER (65 KILOGRAM)

PPB 98 PERCENT

Cl 5.2 LITER / HOUR (EQN)

HT 3 HOUR

SOLUBILITY SOLUBLE IN WATER

3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE (HMG-COA)

3-hydroxy-3-methylglutaryl-coenzyme A reductase UNIPROT P04035 HMGCR

more at DrugCentral

EMA

ANSM (in French)

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Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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