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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| BUDESONIDE
| BUDESONIDE |
RESPIRATORY SYSTEM | NASAL INHALATION ORAL RECTAL | Cmax 2.6 NANOMOLAR Tmax 1.5 HOUR F 9 PERCENT VD 195 LITER (65 KILOGRAM) PPB 87.5 PERCENT Cl 72 LITER / HOUR HT 2.5 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER (LOGP=1.6) | GLUCOCORTICOID RECEPTOR | Glucocorticoid receptor UNIPROT P04150 NR3C1 more at DrugCentral | EMA | |||
