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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FELBAMATE
| FELBAMATE | NERVOUS SYSTEM | ORAL | F 90 PERCENT VD 49.1 LITER (65 KILOGRAM) PPB 25 PERCENT Cl 1.6 LITER / HOUR (65 KILOGRAM) HT 21.5 HOUR SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER | GLUTAMATE [NMDA] RECEPTOR | Glutamate receptor ionotropic, NMDA 2A UNIPROT Q12879 GRIN2A -- Glutamate receptor ionotropic, NMDA 2B UNIPROT Q13224 GRIN2B more at DrugCentral | EMA | |||
