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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DIDANOSINE DISCONTINUED (has an active metabolite)
| DIDANOSINE | ANTIINFECTIVES | ORAL | Tmax 0.8 HOUR F 42 PERCENT VD 70.3 LITER PPB 5 PERCENT Cl 50 LITER / HOUR HT 1.5 HOUR SOLUBILITY IN WATER 27.3 MILLIGRAM / MILLILITER (PH=6) | REVERSE TRANSCRIPTASE (GAG-POL POLYPROTEIN) | Reverse transcriptase,RNaseH UNIPROT Q72549 pol more at DrugCentral | EMA | |||
