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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
TYLOXAPOL DISCONTINUED

TYLOXAPOL


ATC R05CA01

RESPIRATORY SYSTEM
DETERGENTS
SURFACE-ACTIVE AGENTS
EXPECTORANT
PREVENTS THE CATABOLISM OF TRIGLYCERIDES-RICH LIPOPROTEINS BY SERUM LIPASES AND ALLOWS A TIME-DEPENDENT AND LINEAR INCREASE IN PLASMA TRIGLYCERIDES LEVELS

INTRATRACHEAL

PDB 4MGA (CRYSTAL STRUCTURE OF HERA-LBD (Y537S) IN COMPLEX WITH 4-TERT-OCTYLPHENOL)

LIGAND CODE = 27L (link to the list of PDB complexes)

Download experimental 3D coordinates of 27L with added hydrogens

Unknown

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EMA

ANSM (in French)

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SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
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