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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PRAVASTATIN
| PRAVASTATIN |
CARDIOVASCULAR | ORAL | Cmax 62.5 NANOMOLAR Tmax 1.25 HOUR F 17 PERCENT VD 29.9 LITER (65 KILOGRAM) PPB 50 PERCENT Cl 54.6 LITER / HOUR (65 KILOGRAM) HT 1.8 HOUR SOLUBILITY SOLUBLE IN WATER | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE | 3-hydroxy-3-methylglutaryl-coenzyme A reductase UNIPROT P04035 HMGCR more at DrugCentral | EMA | |||
