| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| SOTALOL
| SOTALOL |
CARDIOVASCULAR | ORAL INTRAVENOUS | Tmax 3 HOUR F 95 PERCENT VD 84.5 LITER (65 KILOGRAM) PPB 0 PERCENT Cl 7.8 LITER / HOUR HT 12 HOUR SOLUBILITY SOLUBLE IN WATER | ADRENERGIC BETA RECEPTOR | Beta-1 adrenergic receptor UNIPROT P08588 ADRB1 -- Beta-2 adrenergic receptor UNIPROT P07550 ADRB2 more at DrugCentral | EMA | |||
