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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| EPINEPHRINE (is an active metabolite)
| EPINEPHRINE | NATURAL MOLECULE (link)
METABOLISM | INJECTION INHALATION INTRAMUSCULAR SUBCUTANEOUS IONTOPHORESIS TOPICAL INTRAVENOUS INTRAOCULAR | HT 0.05 HOUR SOLUBILITY SOLUBLE IN WATER | ALPHA ADRENERGIC RECEPTOR BETA ADRENERGIC RECEPTOR PDB 4LDO (STRUCTURE OF BETA2 ADRENOCEPTOR BOUND TO ADRENALINE AND AN ENGINEERED NANOBODY) LIGAND CODE = ALE (link to the list of PDB complexes) Download experimental 3D coordinates of ALE with added hydrogens | Beta-2 adrenergic receptor UNIPROT P07550 ADRB2 -- Alpha-2A adrenergic receptor UNIPROT P08913 ADRA2A more at DrugCentral | EMA | |||
