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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FELODIPINE
| FELODIPINE |
CARDIOVASCULAR | ORAL | Cmax 2 NANOMOLAR Tmax 4.5 HOUR F 20 PERCENT VD 650 LITER (65 KILOGRAM) PPB 99 PERCENT Cl 48 LITER / HOUR HT 14 HOUR SOLUBILITY INSOLUBLE IN WATER | VOLTAGE-DEPENDENT CALCIUM L-CHANNEL | Voltage-dependent L-type calcium channel subunit alpha-1C UNIPROT Q13936 CACNA1C -- Voltage-dependent L-type calcium channel subunit alpha-1D UNIPROT Q01668 CACNA1D more at DrugCentral | EMA | |||
