| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ACITRETIN (is an active metabolite)
| ACITRETIN | DERMATOLOGICALS | ORAL | Cmax 1.27 MICROMOLAR Tmax 2.7 HOUR F 72 PERCENT PPB 99.9 PERCENT HT 49 HOUR | RETINOIC ACID RECEPTOR (RAR) RETINOIC X RECEPTOR (RXR) | Retinoic acid receptor alpha UNIPROT P10276 RARA -- Retinoic acid receptor gamma UNIPROT P13631 RARG more at DrugCentral | EMA | |||
