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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| OMEPRAZOLE
| OMEPRAZOLE ESOMEPRAZOLE |
METABOLISM | ORAL INTRAVENOUS | Cmax 4.09 MICROMOLAR Tmax 2 HOUR F 35 PERCENT VD 16 LITER PPB 95 PERCENT Cl 33 LITER / HOUR HT 0.75 HOUR SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER | H+/K+ ATPASE | Potassium-transporting ATPase UNIPROT P20648 ATP4A more at DrugCentral | EMA | |||
