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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PODOFILOX
| PODOFILOX | NATURAL MOLECULE (link) DERMATOLOGICALS | TOPICAL | Cmax 41 NANOMOLAR HT 2.7 HOUR SOLUBILITY SPARINGLY SOLUBLE IN WATER | PDB 1SA1 (TUBULIN-PODOPHYLLOTOXIN: STATHMIN-LIKE DOMAIN COMPLEX) LIGAND CODE = POD (link to the list of PDB complexes) Download experimental 3D coordinates of POD with added hydrogens | Unknown more at DrugCentral | EMA | |||
