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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LORATADINE (has an active metabolite)
| LORATADINE | RESPIRATORY SYSTEM | ORAL | Cmax 10 NANOMOLAR (PMID18621671) Tmax 1.3 HOUR PPB 98 PERCENT HT 8.4 HOUR SOLUBILITY NOT SOLUBLE IN WATER | HISTAMINE H1 RECEPTOR | Histamine H1 receptor UNIPROT P35367 HRH1 more at DrugCentral | EMA | |||
