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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ZIDOVUDINE

ZIDOVUDINE


ATC J05AF01
ATC J05AR01
ATC J05AR04
ATC J05AR05

ANTIINFECTIVES
ANTIVIRAL
ANTI-HIV
ANTIMETABOLITES
NUCLEOSIDE AND NUCLEOTIDE REVERSE TRANSCRIPTASE (GAG-POL POLYPROTEIN) INHIBITORS

ORAL INJECTION

Tmax 1 HOUR

F 60 PERCENT

VD 104 LITER (65 KILOGRAM)

PPB 38 PERCENT

Cl 104 LITER / HOUR (65 KILOGRAM)

HT 1.75 HOUR

SOLUBILITY OF 20.1 MILLIGRAM / MILLILITER IN WATER AT 25 DEGREE C

HIV REVERSE TRANSCRIPTASE

PDB 3B9L (HUMAN SERUM ALBUMIN COMPLEXED WITH MYRISTATE AND AZT)

LIGAND CODE = AZZ (link to the list of PDB complexes)

Download experimental 3D coordinates of AZZ with added hydrogens

Reverse transcriptase,RNaseH UNIPROT Q72547 pol

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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