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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ENOXACIN DISCONTINUED
| ENOXACIN | ANTIINFECTIVES | ORAL | Cmax 6.2 MICROMOLAR Tmax 2 HOUR F 90 PERCENT VD 130 LITER (65 KILOGRAM) PPB 40 PERCENT Cl 21 LITER / HOUR (65 KILOGRAM) HT 4.5 HOUR | DNA GYRASE | Topoisomerase IV UNIPROT P48374 parC -- DNA gyrase UNIPROT P22118 gyrB more at DrugCentral | EMA | |||
