Cheminformatic Tools and Databases for Pharmacology

session 7313 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
NABUMETONE (has an active metabolite)

NABUMETONE


ATC M01AX01

MUSCULO-SKELETAL
ANTIINFLAMMATORY
NSAID
ANALGESIC
ANTIPYRETIC

ORAL

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

PROSTAGLANDIN G/H SYNTHASE 1
PROSTAGLANDIN G/H SYNTHASE 2

PDB 3TAJ (CRYSTAL STRUCTURE OF C-LOBE OF BOVINE LACTOFERRIN COMPLEXED WITH NABUMETONE AT 1.7A RESOLUTION)

LIGAND CODE = NBO (link to the list of PDB complexes)

Download experimental 3D coordinates of NBO with added hydrogens

Prostaglandin G,H synthase 2 UNIPROT P35354 PTGS2

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |