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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
TERCONAZOLE

TERCONAZOLE


ATC G01AG02

GENITO
ANTIFUNGAL (CANDIDA ALBICANS)
TREATMENT OF VULVOVAGINAL CANDIDIASIS
NHIBITION OF ERGOSTEROL SYNTHESIS AND DISRUPTION OF NORMAL FUNGAL CELL MEMBRANE PERMEABILITY

VAGINAL

Cmax 11 NANOMOLAR

Tmax 6.6 HOUR

F 16 PERCENT

PPB 94.9 PERCENT

HT 6.9 HOUR

SOLUBILITY INSOLUBLE IN WATER

CYTOCHROME P450 14 ALPHA-DEMETHYLASE

Lanosterol 14-alpha demethylase UNIPROT P10613 ERG11

more at DrugCentral

EMA

ANSM (in French)

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