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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PERGOLIDE DISCONTINUED
| PERGOLIDE | NERVOUS SYSTEM | ORAL | Tmax 2.5 HOUR VD 14000 LITER (PMID15965310) PPB 90 PERCENT Cl 462 LITER / HOUR (EQN) HT 21 HOUR | D1 DOPAMINE RECEPTOR D2 DOPAMINE RECEPTOR | D(2) dopamine receptor UNIPROT P14416 DRD2 -- D(1A) dopamine receptor UNIPROT P21728 DRD1 more at DrugCentral | EMA | |||
