| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| NORFLOXACIN DISCONTINUED
| NORFLOXACIN |
ANTIINFECTIVES | ORAL OPHTHALMIC | Cmax 7.5 MICROMOLAR (800 MILLIGRAM) Tmax 1 HOUR F 35 PERCENT HT 3.5 HOUR SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER | DNA GYRASE | DNA topoisomerase 4 subunit A UNIPROT P0AFI2 parC -- DNA gyrase subunit A UNIPROT P0AES4 gyrA more at DrugCentral | EMA | |||
