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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
SELEGILINE

SELEGILINE


ATC N04BD01

NERVOUS SYSTEM
ANTIPARKINSONIAN
ENZYME INHIBITOR MAO
ANTIDYSKINETICS
CENTRAL NERVOUS SYSTEM AGENTS
COVALENT BINDING
ALSO INCREASE DOPAMINERGIC ACTIVITY

ORAL TRANSDERMAL

VD 123.5 LITER (65 KILOGRAM)

PPB 90 PERCENT

Cl 84 LITER / HOUR

HT 2 HOUR (SINGLE DOSE)

SOLUBILITY FREELY SOLUBLE IN WATER

MONOAMINE OXIDASE TYPE B

Amine oxidase flavin-containing B UNIPROT P27338 MAOB

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