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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ISOPROTERENOL
| ISOPROTERENOL |
RESPIRATORY SYSTEM | INHALATION RECTAL SUBLINGUAL INJECTION | VD 97.5 LITER (65 KILOGRAM) PPB 29 PERCENT Cl 218.4 LITER / HOUR (65 KILOGRAM) HT 0.41 HOUR | BETA ADRENERGIC RECEPTOR PDB 4A7T (STRUCTURE OF HUMAN I113T SOD1 MUTANT COMPLEXED WITH ISOPROTERANOL IN THE P21 SPACE GROUP) LIGAND CODE = 5FW (link to the list of PDB complexes) Download experimental 3D coordinates of 5FW with added hydrogens | Beta-1 adrenergic receptor UNIPROT P08588 ADRB1 -- Beta-2 adrenergic receptor UNIPROT P07550 ADRB2 more at DrugCentral | EMA | |||
