| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| GUANFACINE
| GUANFACINE | CARDIOVASCULAR | ORAL | Cmax 10.1 NANOMOLAR Tmax 3 HOUR VD 364 LITER (65 KILOGRAM) PPB 70 PERCENT Cl 17.5 LITER / HOUR (65 KILOGRAM) HT 16 HOUR SOLUBILITY SPARINGLY SOLUBLE IN WATER | ALPHA-2A ADRENERGIC RECEPTOR | Alpha-2A adrenergic receptor UNIPROT P08913 ADRA2A more at DrugCentral | EMA | |||
