FLUOXETINE (has an active metabolite) | FLUOXETINE | ATC N06AB03 ATC N06CA03
NERVOUS SYSTEM ANTIDEPRESSANT SELECTIVE SEROTONIN REUPTAKE INHIBITORS (SSRIS) INHIBITION OF CNS NEURONAL UPTAKE OF SEROTONIN | ORAL | Cmax 178 NANOMOLAR Tmax 7 HOUR VD 1950 LITER (65 KILOGRAM) PPB 94.5 PERCENT HT 120 HOUR SOLUBILITY 14 MILLIGRAM / MILLILITER | SODIUM-DEPENDENT SEROTONIN TRANSPORTER POTASSIUM CHANNEL TREKS PDB 4MM8 (CRYSTAL STRUCTURE OF LEUBAT (DELTA13 MUTANT) IN COMPLEX WITH (R)-FLUOXETINE) LIGAND CODE = RFX (link to the list of PDB complexes) Download experimental 3D coordinates of RFX with added hydrogens | Sodium-dependent serotonin transporter UNIPROT P31645 SLC6A4 more at DrugCentral | EMA ANSM (in French) Inxight Drugs Dailymed Drugs.com SIDER side effects Chemical Probes Portal ChEMBL BindingDB DrugBank |