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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ACEBUTOLOL (has an active metabolite)
| ACEBUTOLOL | CARDIOVASCULAR | ORAL | Tmax 2.5 HOUR F 40 PERCENT VD 102 LITER PPB 26 PERCENT Cl 36 LITER / HOUR HT 3.5 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | BETA-1 ADRENERGIC RECEPTOR | Beta-1 adrenergic receptor UNIPROT P08588 ADRB1 more at DrugCentral | EMA | |||
