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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PRAZIQUANTEL
| PRAZIQUANTEL | ANTIPARASITIC | ORAL | Cmax 2.6 MICROMOLAR Tmax 2 HOUR F 80 PERCENT PPB 80 PERCENT HT 1.1 HOUR SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER | GLUTATHIONE S-TRANSFERASE PDB 1GTB (GLUTATHIONE S-TRANSFERASE FROM SCHISTOSOMA JAPONICA) | High voltage-activated calcium channel beta subunit CavB1 UNIPROT Q95US7 -- High voltage-activated calcium channel beta subunit CavB2 UNIPROT Q962H3 more at DrugCentral | EMA | |||
