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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| QUAZEPAM
| QUAZEPAM | NERVOUS SYSTEM | ORAL | Cmax 51.7 NANOMOLAR Tmax 2 HOUR PPB 95 PERCENT HT 39 HOUR SOLUBILITY INSOLUBLE IN WATER | GAMMA-AMINOBUTYRIC-ACID RECEPTOR | GABA A receptor alpha-1,beta-1,gamma-2 UNIPROT P14867 GABRA1 -- GABA A receptor alpha-3,beta-1,gamma-2 UNIPROT P18505 GABRB1 more at DrugCentral | EMA | |||
