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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| INDAPAMIDE
| INDAPAMIDE |
CARDIOVASCULAR | ORAL | Cmax 711.5 NANOMOLAR Tmax 2 HOUR F 100 PERCENT PPB 75 PERCENT HT 14 HOUR SOLUBILITY IS SOLUBLE IN AQUEOUS SOLUTIONS OF STRONG BASES | ION CHANNELS PDB 3BL1 (CARBONIC ANHYDRASE INHIBITORS. SULFONAMIDE DIURETICS REVISITED OLD LEADS FOR NEW APPLICATIONS) LIGAND CODE = BL1 (link to the list of PDB complexes) Download experimental 3D coordinates of BL1 with added hydrogens | Solute carrier family 12 member 3 UNIPROT P55017 SLC12A3 more at DrugCentral | EMA | |||
