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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
TEMAZEPAM (is an active metabolite) (has an active metabolite)

TEMAZEPAM


ATC N05CD07

NERVOUS SYSTEM
HYPNOTICS AND SEDATIVES
BENZODIAZEPINES
GABA MODULATORS
ALLOSTERIC POSITIVE

ORAL

Cmax 2.7 MICROMOLAR

F 92 PERCENT

PPB 96 PERCENT

HT 8.8 HOUR

SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER

GABA RECEPTOR

GABA-A receptor alpha-1,beta-2,gamma-2 UNIPROT P14867 GABRA1

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