| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PIROXICAM
| PIROXICAM |
MUSCULO-SKELETAL SYSTEM | ORAL | Cmax 24 MICROMOLAR Tmax 4 HOUR VD 9.1 LITER (65 KILOGRAM) PPB 99 PERCENT Cl 0.12 LITER / HOUR (EQN) HT 50 HOUR SOLUBILITY SLIGHTLY SOLUBLE IN WATER | PROSTAGLANDIN G/H SYNTHASE | Prostaglandin G,H synthase 2 UNIPROT P35354 PTGS2 -- Prostaglandin G,H synthase 1 UNIPROT P23219 PTGS1 more at DrugCentral | EMA | |||
