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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ALPHA-TOCOPHEROL (is an active metabolite)
| ALPHA-TOCOPHEROL VITAMIN E TOCOPHEROL | NATURAL MOLECULE (link) METABOLISM | INJECTION INTRAVENOUS | ALPHA-TOCOPHEROL TRANSFER PROTEIN (ALPHA-TTP) (PMID24231105) PDB 5MUG (SELF-ASSEMBLED ALPHA-TOCOPHEROL TRANSFER PROTEIN NANOPARTICLES PROMOTE VITAMIN E DELIVERY ACROSS AN ENDOTHELIAL BARRIER) LIGAND CODE = VIV (link to the list of PDB complexes) Download experimental 3D coordinates of VIV with added hydrogens | Glutathione S-transferase P UNIPROT P09211 -- Alpha-tocopherol transfer protein UNIPROT P49638 more at DrugCentral | EMA | ||||
