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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| NALBUPHINE
| NALBUPHINE | NERVOUS SYSTEM | INJECTION | Tmax 0.041 HOUR VD 299 LITER (65 KILOGRAM) PPB 50 PERCENT Cl 85.8 LITER / HOUR (65 KILOGRAM) HT 5 HOUR SOLUBILITY 35.5 MILLIGRAM / MILLILITER IN WATER (25 DEGREE CELCIUS) | DELTA-TYPE OPIOID RECEPTOR KAPPA-TYPE OPIOID RECEPTOR MU-TYPE OPIOID RECEPTOR | Mu-type opioid receptor UNIPROT P35372 OPRM1 -- Kappa-type opioid receptor UNIPROT P41145 OPRK1 more at DrugCentral | EMA | |||
